Discoveries in the biomedical sciences and innovations in clinical medicine have led to significant victories in our longstanding war against disease and suffering. With the mapping of the entire human genome, we are now closer to the understanding of the mechanisms of life, aging, illness and death, opening up exciting new opportunities for advances in therapeutics. Novel insights in the life science and technological advances in medicine will result in better health and an improved quality of life for the human race in the new century.
for their discovery of the genetic and molecular mechanisms underlying the fetal-to-adult hemoglobin switch, making possible a revolutionary and highly effective genome-editing therapy for sickle cell anemia and β thalassemia, devastating blood diseases that affect millions of people worldwide.
Prizes in Life Science and Medicine have been awarded to one laureate only
Prizes in Life Science and Medicine have been shared by two laureates
Prizes in Life Science and Medicine have been shared by three laureates
for their contributions to the understanding of the molecular mechanism of protein folding. Proper protein folding is essential for many cellular functions.
for their discovery of the molecular mechanism of innate immunity, the first line of defense against pathogens.
for his seminal discoveries of molecular mechanisms by which the skin senses painful stimuli and temperature and produces pain hypersensitivity.
for their work leading to the discovery of leptin, a hormone that regulates food intake and body weight
for their recent pivotal innovations in reversing the process of cell differentiation in mammals, a phenomenon which advances our knowledge of developmental biology and holds great promise for the treatment of human diseases and improvements in agriculture practices.
for his relentless elucidation of the major receptor system that mediates the response of cells and organs to drugs and hormones.
