for his ground-breaking discoveries about millisecond pulsars, gamma-ray bursts, supernovae, and other variable or transient astronomical objects. His contributions to time-domain astronomy culminated in the conception, construction and leadership of the Palomar Transient Factory and its successor, the Zwicky Transient Facility, which have revolutionised our understanding of the time-variable optical sky.
for their discovery of the genetic and molecular mechanisms underlying the fetal-to-adult hemoglobin switch, making possible a revolutionary and highly effective genome-editing therapy for sickle cell anemia and β thalassemia, devastating blood diseases that affect millions of people worldwide.
for his development of the arithmetic theory of thin groups and the affine sieve, by bringing together number theory, analysis, combinatorics, dynamics, geometry and spectral theory.
for the discovery of fast radio bursts (FRBs).
for pioneering structural biology that enabled visualisation, at the level of individual atoms, of the protein machines responsible for gene transcription, one of life’s fundamental processes. They revealed the mechanism underlying each step in gene transcription, how proper gene transcription promotes health, and how dysregulation causes disease.
for their contributions related to mathematical physics, to arithmetic geometry, to differential geometry and to Kähler geometry.
